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Tuesday, February 10, 2009

SIR FREDRICK GRANT BANTING

SIR FREDRICK GRANT BANTING
( 1891 - 1941 )

Banting was the Canadian physician. He was a medicinal scientist. He extracted the insulin hormone from the Pancreas. Insulin is a protein hormone which is produced by the islets of Langerhans of the Pancreas. It is widely used in the treatment of diabetes mellitus. Banting’s research made it possible to prolong the lives of the victims of diabetes. Otherwise they were facing death as the level of glucose accumulation in the blood stream was to be higher. Banting isolated insulin in a fantastic way. His assistant was Best. Both tied the Pancreatic duets of several dogs for a period of seven weeks, after which the Pancreas crumbled up and were functionless as digestive organs. The is bets of Langerhans remained intact and a solution was extracted from these cells. Banting and Best did their work in the laboratory of John J.R. Macleod at the university of Toronto. Macleod didn’t participate in the work. But still Nobel Prize in physiology and medicine was awarded to both in 1923. They shared where as Best didn’t get anything. But Banting sent half of the award amount to his assistant charles H. Best. They demonstrated the role of insulin in controlling the blood sugar levels. Insulin injection results promptly in decline in blood glucose concentration and an increase in formation of products derived from glucose.

Banting died in 1941.

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